Lipogems is Not a Stem Cell Therapy ~ Mesenchymal Stromal Cells  vs. Mesenchymal Stem Cells

Click on the links below for the following papers regarding MSC criteria and features:
Mammalian MSC from selected species: Features and applications.

Uder C1, Brückner S1, Winkler S1, Tautenhahn HM1, Christ B.

Click here to read the abstract and download the paper.

Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement.

Dominici M1, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini F, Krause D, Deans R, Keating A, Prockop Dj, Horwitz E.

Click here to read the abstract and download the paper.

For further reading and papers relating to Lipogems application please click here to download a selection of studies.

Damage Response Mechanism

Lipogems® Preserves viable elements with Pericyte identity which, after an injury detach from the capillaries and gradually convert into activated Mesenchymal Stromal Cells (MSCs). The Lipogems® process acts as a replica of damage to cells in a trauma situation encouraging cells to behave as if an injury has occurred.


What is Regenerative Tissue Engineering?
Regeneration vs repair of tissues is the central logic for the field of Regenerative Engineering.

Cell Characterisation

Lipogems® Contains more Mesenchymal Stromal Cells (MSCs), Pericytes and Transitional Pericytes than Lipoaspirate. Due to the intact vascular stromal niche Lipogems® acts as a natural scaffold preserving activated MSCs.

Professor Caplan is “The father of the MSC”, explains in this clip how this new branch of science works.

Professor Arnold I. Caplan, Ph.D (2008)

"You are ALIVE because you continuously renew (rejuvenate) various tissues/organs. Within the body, cells of the skin, gut, and blood, among others come to maturation, function for a time and then expire to be replaced by a continuous stream of cells which renew the tissue."

Skeletal Research Center, Case Western Reserve University and NJ Symp Biomat & Regen Med 

Pericytes in Adipose Tissue 

Pericytes exist in adipose tissue niche wrapped around capillaries within adipocyte clusters; Pericytes react to signals from injury or damage  

The Science of Lipogems® 

Bianchi, Francesca, et al. “A new nonenzymatic method and device to obtain a fat tissue derivative highly enriched in pericyte-like elements by mild mechanical forces from human lipoaspirates.” Cell transplantation 22.11 (2013): 2063-2077.

Lipocast Biotech UK Ltd, as the distributor and training centre for Lipogems® Equine takes the science of Lipogems® International SPA and has shown that its application from hundreds of trials in human medicine has had huge success in the treatment of a range of common, sometimes career ending injuries and diseases in horses and ponies. There is a huge amount of science and research behind what the Lipogems® Equine team are able to apply to your horse or pony. Here are just some of the more in depth details about how the science works. To see the outcomes of some of the cases that have been treated in the UK click here. To read the full scientific story of Lipogems® click here to visit the Lipogems® International SPA website. If you are a vet and would like to read our comprehensive presentation on the science behind Lipogems® Equine complete with case studies and links for further reading click here.

Lipogems  EQUINE